450 projects straddling discovery through development in PK Sciences (PKS) for you to represent the clinical pharmacology and PK/PD/ADME disciplines on discovery and development project teams. As a project team member, you will suggest and implement strategies and tactics to advance high-quality entities as part of the overall program(s).
PK Sciences (PKS) is a global organization of about 300 associates, situated within Translational Medicine (TM), the clinical research arm of NIBR. PK Sciences plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, bridging drug discovery and clinical application. PK Science is an enterprise organization, working across both NIBR and the Global Drug Development (GDD) organizations to advance the scientific knowledge of pharmacokinetics, metabolism and clinical pharmacology from discovery through approval and beyond.
In the role of Principal Scientist, PKS Oncology, you will develop and implement clinical pharmacology strategies to support small and large molecule drug development from early discovery through late clinical development. This unique role will provide matrix leadership to collaborate, align and influence across the cross-functional team to identify and mitigate key project issues related to the pharmacokinetic sciences discipline (clinical pharmacology and PK, PK/PD, metabolism).
In addition, you will be responsible for the PK, PK/PD and M&S component of study protocols, reports, project summaries and development plans, and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections of IND/IMPDs and NDA/BLAs to meet regulatory requirements as well as prepare appropriate responses to Health Authority questions across the globe. You will have the opportunity to oversee or perform PK and PK/PD analyses using a variety of tools and approaches and integrate, interpret and report data to project teams and other customers.